Zollinger-Ellison Syndrome Symptoms
Zollinger-Ellison Syndrome symptoms may be severe and persistent, and you may find that taking over-the-counter antacids provides you little or no relief, even temporarily.
Zollinger-Ellison syndrome is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum. The pancreas is a gland located behind the stomach. It produces enzymes that break down fat, protein, and carbohydrates from food, and hormones like insulin that break down sugar. The duodenum is the first part of the small intestine.
The pancreas tumors secrete a hormone called gastrin that causes the stomach to produce too much acid, which in turn causes stomach and duodenal ulcers (peptic ulcers). The ulcers caused by
Zollinger-Ellison syndromare less responsive to treatment than ordinary peptic ulcers. What causes people with
Zollinger-Ellison syndrom to develop tumors is unknown, but approximately 25 percent of
Zollinger-Ellison syndrom cases are associated with a genetic disorder called multiple endocrine neoplasia type 1, which is associated with additional disorders.
Symptoms of Zollinger-Ellison Syndrome
- Diarrhea
- Weight loss
- Burning, aching, gnawing or discomfort in your upper abdomen
- Nausea and vomiting
- Fatigue
If you have Zollinger-Ellison syndrome, earlier detection and treatment may
be able to halt the spread of any malignant pancreas tumors to other organs or lymph
nodes.
Zollinger-Ellison Syndrome Symptoms
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